Thirteen years ago in the New Common Era (新西暦, Shinseireki) calendar, the computer controlling the newly discovered energy source called Enetron (エネトロン, Enetoron) was infected by a virus that caused it to create the evil energy being known as Messiah who wishes to take over mankind and create a world made for machines.
Though sent into subspace by the scientists’ sacrifice, Messiah’s actions established the formation of the Energy Management Center’s Special Ops Unit from three children who were caught in the crossfire, the Go-Busters, and their Buddyloids.
[Note 1] In the present, 2012 NCE, a mysterious figure named Enter leads a group called Vaglass on incursions to gather enough Enetron to bring Messiah back.
However, training for this day, the Go-Busters and their Buddyloids are deployed to combat Vaglass’s Metaloids and Megazords to protect the city’s Enetron from them.
Later joined by Masato Jin and his Buddyloid Beet J. Stag, the Go-Busters’ resolve is strengthened once they learn the true nature of their enemy and the horrors that would result should Messiah enter their world.